Autism

Demographics

2–6 per 10,000. M>F.

Diagnosis

1 A, 1 B, 1 C.
  1. Impaired reciprocal social interaction (A symptoms)
  2. Impaired imagination (B symptoms)
  3. Poor range of activities and interests (C symptoms)

Differential diagnosis

Causes

  1. Fragile X syndrome
  2. Tuberous sclerosis
  3. phenylketonuria
  4. neurofibromatosis
  5. hypomelanosis of Ito
There is no association with Down syndrome or cerebral palsy. 25–30% associated with epilepsy