Inflammatory Bowel Disease

Collective term for Crohn's Disease and ulcerative colitis.

Crohn's Disease

Treatment

Ulcerative colitis

Treatment

Steroids and 5-ASA compounds can be used in pregnancy.

Differences

Crohn'sUC
affects terminal ileumaffects rectum (never affects small bowel)
skip lesionslesions contiguous
cobble stone mucosa (rose thorn ulcers on Ba enema)pseudopolyps
transmural inflammationinflammation confined to mucosa
fistulaeno fistulae
granulomatacrypt abcesses
goblet cells normalreduced goblet cells
It is sometimes impossible to distinguish between the two (biopsy shows only inflammation).