Viral Hepatitis

Hepatitis A

20% develop acute hepatitis (flu-like symptoms, jaundice). 85% people develop chronic hepatitis C. 20–30% develop cirrhosis in 20 years.

Severe disease: Ribavirin + INFα (NICE 31 Oct 2000) 2/3 respond to 24/52 treatment. Severity judged by liver biopsy.
End stage disease: Liver transplant