Jaundice

Scleral icterus clinical visible >34 µM.
Unconjugated hyperbilirubinaemia: urine not dark.
Conjugated hyperbilirubinaemia: urine dark.
Obstructive jaundice: urine dark, stool pale. Bile: conjugated bilirubin, .

Causes

Prehepatic
  1. Haemolysis
  2. Gilbert's syndrome
  3. Crigler-Najjar syndrome
Hepatic
  1. EtOH
  2. viral
  3. PBC
Posthepatic
  1. gallstone
  2. Ca head pancreas
  3. periampullary Ca, cholangiocarcinoma
  4. cholangitis